LD LASSO Regression for SNP Association Study


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Documentation for package ‘ldlasso’ version 3.2

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ldlasso-package LD LASSO for Case Control Genetic Association Study
block.bounds Creates a vector of haplotype block boundary basepair positions.
block.cood Vector of Haplotype Block Boundaries
block.map.matrix Creates an indicator matrix for haplotype block boundaries, for use in ld_lasso.
block.obj GenABEL Object with Genotype and Phenotype Data
blockcood Vector of Haplotype Block Boundaries
blockobj GenABEL Object with Genotype and Phenotype Data
chi2 Creates a vector of chi-squared values from the allelic test of association
get.cp Uses bootstrap sampling over a vector of LD LASSO constraint parameters, s2, to compute a vector of cp estimates.
get.s1 Finds an estimate for s1 based on an estimate of the expected false positive rate. This function is a wrapper for p0tos1.
heatmap Plots the heat map for the LD LASSO solution space
ldlasso LD LASSO for Case Control Genetic Association Study
ldlasso.obj LD LASSO Object created by the function ld_lasso_method
ldlassoobj LD LASSO Object created by the function ld_lasso_method
ld_lasso The main function of the LD LASSO method
ld_lasso_method The LD LASSO function
p0tos1 Finds the LASSO parameter s1 that corresponds to desired false positive rate
plot_beta Plot the LD LASSO solution by physical position.
plot_ldlasso Diagnostic plot for an ldlasso object
plot_ld_lasso Diagnostic plot for an ldlasso object
plot_ld_lasso_method Diagnostic plot for an ldlasso object
r2.cut.fn Find the r-squared cutoff
trace.plot Creates a trace plot for the LD LASSO