PAGWAS-package |
Pathway analysis methods for genomewide association data |
create.pathway.matrix |
Creates a pathway matrix |
FM.chi.pvalue |
Calculates the Fisher's method p-value for each tested pathway |
genes |
A data-frame of 20 genes with their chromosomes and positions on the genome |
genotypes |
Genotypes for 100 SNPs |
list.of.parameters |
A list with possible hyper-parameters for NBF |
NBF |
Normal/Bayes factors (NBF) method for finding associated pathways |
PAGWAS |
Pathway analysis methods for genomewide association data |
pathways |
A list of 2 pathways with their gene members |
return.a.SNAL |
Returns the hyper-parameter a of SNAL |
return.bf.NBF |
Returns the Bayes factor threshold of NBF |
return.hyperparameters.NBF |
Returns the four hyper-parameters of NBF |
return.s2.SNAL |
Returns the s2 tuning parameter of SNAL |
roc.convex |
Computes the area under a ROC curve |
SNAL |
Sparse Normal/Adaptive lasso (SNAL) method for finding associated pathways |
SNPs |
A data-frame of 100 SNPs with their chromosomes and positions on the genome |
snps.to.genes |
Assigns SNPs to genes according to their physical distance |
snps.to.pathways |
Assigns SNPs to pathways |