Transmission Ratio Distortion


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Documentation for package ‘TRD’ version 1.0

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TRD-package Transmission Ratio Distortion
find.maf Find MAF of sample of case-trios and control-trios
findr Find transmission ratio of minor alleles.
gcount Calculate genotype counts from trios dataset
ll Fit Loglinear model with and without adjustment for TRD.
prev Calculate prevalence of disease
rtrios Generate simulated popoulation of case- and control-trios
strata.cnt Count trios for each of 15 strata with mother-father-child genotypes
tdt Compute TDT and augmented TDT on trios
tdt.cnt Count transmission of allele in McNemar Table
TRD Transmission Ratio Distortion