A Bayesian Dose-Finding Design using Pharmacokinetics(PK) for Phase I Clinical Trials

Documentation for package ‘dfpk’ version 1.0

dfpk-package	A Bayesian Dose-Finding Design using Pharmacokinetics(PK) for Phase I Clinical Trials.
AUC_estim	Estimation of the area under the curve, AUC.
dfpk	A Bayesian Dose-Finding Design using Pharmacokinetics(PK) for Phase I Clinical Trials.
dosefinding-class	An S4 class to represent a dosefinding results.
dtox	Dose finding method DTOX
invlogit	Inverse logistic functions
nsim	More than one simulation using PK measure in the dose finding design
pk.estim	PK measure of exposure
pkcov	Dose finding method PKCOV
pkcrm	Dose finding method PKCRM
pklogit	Dose finding method PKLOGIT
pkpop	Dose finding method PKPOP
pktox	Dose finding method PKTOX
plotConc	The generic function of plot.conc
plotConc-method	The graphical representation of the drug's concentration in the plasma at time t after the drug administration.
plotDose	The generic function of the plot.dose
plotDose-method	The graphical representation of dose escalation for each patient in the trial.
scen-class	An S4 class to represent a simulated scenarios.
scenarios	Generate New Scenarios
show-method	S4 Methods for Function 'show'
show-methods	S4 Methods for Function 'show'
sim	One simulation using PK measure in the dose finding design.
stan_f	The data stan_f includes all the Stan models that dfpk package uses.