Tools for Nonlinear Mixed-Effect Model Building and Diagnostics


[Up] [Top]

Documentation for package ‘xpose4’ version 4.5.3

Help Pages

A B C D E F G I K L M N P R S T V W X

xpose4-package The Xpose Package
xpose4classic-package Xpose classic menu system
xpose4data-package Xpose database creation and manipulation
xpose4generic-package Xpose generic multi-purpose functions
xpose4psn-package Xpose PsN post-processing functions
xpose4specific-package Xpose specific functions for a single purpose

-- A --

absval.cwres.vs.cov.bw Absolute conditional weighted residuals vs covariates for Xpose 4
absval.cwres.vs.pred Absolute population conditional weighted residuals vs population predictions for Xpose 4
absval.cwres.vs.pred.by.cov Absolute value of the conditional weighted residuals vs. population predictions, conditioned on covariates, for Xpose 4
absval.dcwres.vs.cov.model.comp Model comparison plots, of absolute differences in goodness-of-fit predictors against covariates, for Xpose 4
absval.dipred.vs.cov.model.comp Model comparison plots, of absolute differences in goodness-of-fit predictors against covariates, for Xpose 4
absval.diwres.vs.cov.model.comp Model comparison plots, of absolute differences in goodness-of-fit predictors against covariates, for Xpose 4
absval.dpred.vs.cov.model.comp Model comparison plots, of absolute differences in goodness-of-fit predictors against covariates, for Xpose 4
absval.dwres.vs.cov.model.comp Model comparison plots, of absolute differences in goodness-of-fit predictors against covariates, for Xpose 4
absval.iwres.cwres.vs.ipred.pred Absolute population weighted residuals vs population predictions, and absolute individual weighted residuals vs individual predictions, for Xpose 4
absval.iwres.vs.cov.bw Absolute weighted residuals vs covariates for Xpose 4
absval.iwres.vs.idv Absolute individual weighted residuals vs population predictions or independent variable for Xpose 4
absval.iwres.vs.ipred Absolute individual weighted residuals vs individual predictions for Xpose 4
absval.iwres.vs.ipred.by.cov Absolute individual weighted residuals vs individual predictions, conditioned on covariates, for Xpose 4
absval.iwres.vs.pred Absolute individual weighted residuals vs population predictions or independent variable for Xpose 4
absval.iwres.wres.vs.ipred.pred Absolute population weighted residuals vs population predictions, and absolute individual weighted residuals vs individual predictions, for Xpose 4
absval.wres.vs.cov.bw Absolute weighted residuals vs covariates for Xpose 4
absval.wres.vs.idv Absolute value of (C)WRES vs. independent variable plot in Xpose4.
absval.wres.vs.pred Absolute population weighted residuals vs population predictions for Xpose 4
absval.wres.vs.pred.by.cov Absolute population weighted residuals vs population predictions, conditioned on covariates, for Xpose 4
add.absval Column-transformation functions for Xpose 4
add.dichot Column-transformation functions for Xpose 4
add.exp Column-transformation functions for Xpose 4
add.grid.table Print tables or text in a grid object
add.grid.text Print tables or text in a grid object
add.log Column-transformation functions for Xpose 4
add.model.comp Additional model comparison plots, for Xpose 4
add.modify.db.items.menu Classic menu functions for Xpose 4
add.tad Column-transformation functions for Xpose 4
addid Generic internal functions for Xpose 4
addit.gof Additional goodness-of-fit plots, for Xpose 4
another.menu Classic menu functions for Xpose 4
autocorr.cwres Autocorrelation of conditional weighted residuals for Xpose 4
autocorr.iwres Autocorrelation of weighted residuals for Xpose 4
autocorr.wres Autocorrelation of weighted residuals for Xpose 4

-- B --

basic.gof Basic goodness-of-fit plots, for Xpose 4
basic.model.comp Basic model comparison plots, for Xpose 4
boot.hist Function to create histograms of results from the 'bootstrap' tool in PsN
bootgam.print Print summary information for a bootgam or bootscm
bootscm.import Import bootscm data into R/Xpose

-- C --

calc.npar Read NONMEM output files into Xpose 4
cat.dv.vs.idv.sb Categorical observations vs. idependent variable using stacked bars.
cat.pc Categorical (visual) predictive check.
categorical.table Generic table functions for Xpose 4
change.ab.graph.par Functions changing variable definitions in Xpose 4
change.bw.graph.par Functions changing variable definitions in Xpose 4
change.cat.cont Functions changing miscellaneous parameter settings in Xpose 4
change.cat.cont<- Functions changing miscellaneous parameter settings in Xpose 4
change.cat.levels Functions changing miscellaneous parameter settings in Xpose 4
change.cat.levels<- Functions changing miscellaneous parameter settings in Xpose 4
change.cond.graph.par Functions changing variable definitions in Xpose 4
change.dil.graph.par Functions changing variable definitions in Xpose 4
change.dispersion Classic menu functions for Xpose 4
change.dv.cat.levels Functions changing miscellaneous parameter settings in Xpose 4
change.dv.cat.levels<- Functions changing miscellaneous parameter settings in Xpose 4
change.graphical.par Classic menu functions for Xpose 4
change.label.par Functions changing variable definitions in Xpose 4
change.lm.graph.par Functions changing variable definitions in Xpose 4
change.medianNorm Classic menu functions for Xpose 4
change.misc.graph.par Functions changing variable definitions in Xpose 4
change.miss Functions changing miscellaneous parameter settings in Xpose 4
change.onlyfirst Classic menu functions for Xpose 4
change.parm Change parameter scope.
change.pi.graph.par Functions changing variable definitions in Xpose 4
change.smooth.graph.par Functions changing variable definitions in Xpose 4
change.steppit Classic menu functions for Xpose 4
change.subset Functions changing miscellaneous parameter settings in Xpose 4
change.use.ids Classic menu functions for Xpose 4
change.var.name Changes the name of an Xpose data item
change.xlabel Changes the label of an Xpose data item
change.xp.obj Classic menu functions for Xpose 4
change.xvardef Change Xpose variable definitions.
change.xvardef<- Change Xpose variable definitions.
check.gamobj GAM functions for Xpose 4
check.vars Data functions for Xpose 4
compute.cwres Compute the Conditional Weighted Residuals
computePI Generic internal functions for Xpose 4
continuous.table Generic table functions for Xpose 4
cov.hist Plot the parameter or covariate distributions using a histogram
cov.qq Plot the parameter or covariate distributions using quantile-quantile (Q-Q) plots
cov.splom Plot scatterplot matrices of parameters, random parameters or covariates
cov.summary Summarize individual parameter values and covariates
covariate.model.menu Classic menu functions for Xpose 4
create.mirror Function to create mirror plots from the generic Xpose plotting commands
create.parameter.list Read NONMEM output files into Xpose 4
create.rand Generic internal functions for Xpose 4
create.strat.rand Generic internal functions for Xpose 4
create.xpose.plot.classes Create xpose.multiple.plot class.
createXposeClasses This function creates the Xpose data classes ("xpose.data" and "xpose.prefs")
cwres.dist.hist Histogram of conditional weighted residuals (CWRES), for Xpose 4
cwres.dist.qq Quantile-quantile plot of conditional weighted residuals (CWRES), for Xpose 4
cwres.menu Classic menu functions for Xpose 4
cwres.vs.cov Conditional Weighted residuals (CWRES) plotted against covariates, for Xpose 4
cwres.vs.idv Population conditional weighted residuals (CWRES) plotted against the independent variable (IDV) for Xpose 4
cwres.vs.idv.bw Box-and-whisker plot of conditional weighted residuals vs the independent variable for Xpose 4
cwres.vs.pred Population conditional weighted residuals (CWRES) plotted against population predictions (PRED) for Xpose 4
cwres.vs.pred.bw Box-and-whisker plot of conditional weighted residuals vs population predictions for Xpose 4
cwres.wres.vs.idv Weighted residuals (WRES) and conditional WRES (CWRES) plotted against the independent variable (IDV) or the population predictions (PRED) for Xpose 4
cwres.wres.vs.pred Weighted residuals (WRES) and conditional WRES (CWRES) plotted against the independent variable (IDV) or the population predictions (PRED) for Xpose 4

-- D --

Data Extract data from an xpose.data object.
data.checkout Check through the source dataset to detect problems
data.checkout.menu Classic menu functions for Xpose 4
Data<- Extract data from an xpose.data object.
db.names Prints the contents of an Xpose data object
documentation.menu Classic menu functions for Xpose 4
dOFV.vs.cov Change in individual objective function value vs. covariate value.
dOFV.vs.id Change in Objective function value vs. removal of individuals.
dOFV1.vs.dOFV2 Change in individual objective function value 1 vs. individual objective function value 2.
dv.preds.vs.idv Observations (DV), individual predictions (IPRED) and population predictions (IPRED) plotted against the independent variable (IDV), for Xpose 4
dv.vs.idv Observations (DV) plotted against the independent variable (IDV) for Xpose 4
dv.vs.ipred Observations (DV) plotted against individual predictions (IPRED) for Xpose 4
dv.vs.ipred.by.cov Dependent variable vs individual predictions, conditioned on covariates, for Xpose 4
dv.vs.ipred.by.idv Dependent variable vs individual predictions, conditioned on independent variable, for Xpose 4
dv.vs.pred Observations (DV) plotted against population predictions (PRED) for Xpose 4
dv.vs.pred.by.cov Dependent variable vs population predictions, conditioned on covariates, for Xpose 4
dv.vs.pred.by.idv Dependent variable vs population predictions, conditioned on independent variable, for Xpose 4
dv.vs.pred.ipred Observations (DV) are plotted against individual predictions (IPRED) and population predictions (PRED), for Xpose 4

-- E --

eq.xpose Generic internal functions for Xpose 4
export.graph.par Exports Xpose graphics settings to a file.
export.variable.definitions Exports Xpose variable definitions to a file from an Xpose data object.

-- F --

find.right.table Internal functions for the VPC
fix.wrapped.lines Read NONMEM output files into Xpose 4

-- G --

gam.change.weights Classic menu functions for Xpose 4
gam.menu Classic menu functions for Xpose 4
gam.settings.menu Classic menu functions for Xpose 4
get.doc Functions changing miscellaneous parameter settings in Xpose 4
get.polygon.regions Internal functions for the VPC
get.refrunno Generic internal functions for Xpose 4
gof Structured goodness of fit diagnostics.
gof.menu Classic menu functions for Xpose 4
gofSetup Structured goodness of fit diagnostics.

-- I --

import.graph.par Imports Xpose graphics settings from a file to an Xpose data object.
import.variable.definitions Imports Xpose variable definitions from a file to an Xpose data object.
ind.cwres Compute the Conditional Weighted Residuals
ind.plots Observations (DV), individual predictions (IPRED) and population predictions (PRED) are plotted against the independent variable for every individual in the dataset, for Xpose 4
ind.plots.cwres.hist Histograms of weighted residuals for each individual in an Xpose data object, for Xpose 4
ind.plots.cwres.qq Quantile-quantile plots of weighted residuals for each individual in an Xpose data object, for Xpose 4
ind.plots.wres.hist Histograms of weighted residuals for each individual in an Xpose data object, for Xpose 4
ind.plots.wres.qq Quantile-quantile plots of weighted residuals for each individual in an Xpose data object, for Xpose 4
ipred.vs.idv Individual predictions (IPRED) plotted against the independent variable (IDV) for Xpose 4
is.cwres.readable.file Compute the Conditional Weighted Residuals
is.readable.file Data functions for Xpose 4
iwres.dist.hist Histogram of individual weighted residuals (IWRES), for Xpose 4
iwres.dist.qq Quantile-quantile plot of individual weighted residuals (IWRES), for Xpose 4
iwres.vs.idv Individual weighted residuals (IWRES) plotted against the independent variable (IDV) for Xpose 4

-- K --

kaplan.plot Kaplan-Meier plots of (repeated) time-to-event data

-- L --

list.gam.settings Classic menu functions for Xpose 4

-- M --

main.menu Classic menu functions for Xpose 4
make.sb.data Make stacked bar data set.
manage.db Classic menu functions for Xpose 4
model.comparison.covariates.menu Classic menu functions for Xpose 4
model.comparison.menu Classic menu functions for Xpose 4

-- N --

npc.coverage Function to plot the coverage of the Numerical Predictive Check
nsim Extract or set the value of the Nsim slot.
nsim<- Extract or set the value of the Nsim slot.

-- P --

parameters.menu Classic menu functions for Xpose 4
parm.hist Plot the parameter or covariate distributions using a histogram
parm.qq Plot the parameter or covariate distributions using quantile-quantile (Q-Q) plots
parm.splom Plot scatterplot matrices of parameters, random parameters or covariates
parm.summary Summarize individual parameter values and covariates
parm.vs.cov Parameters plotted against covariates, for Xpose 4
parm.vs.parm Plot parameters vs other parameters
pred.vs.idv Population predictions (PRED) plotted against the independent variable (IDV) for Xpose 4
preferences.menu Classic menu functions for Xpose 4
print-method Create xpose.multiple.plot class.
print.xpose.multiple.plot Print an Xpose multiple plot object.

-- R --

randtest.hist Function to create a histogram of results from the randomization test tool ('randtest') in PsN
ranpar.hist Plot the parameter or covariate distributions using a histogram
ranpar.qq Plot the parameter or covariate distributions using quantile-quantile (Q-Q) plots
ranpar.splom Plot scatterplot matrices of parameters, random parameters or covariates
ranpar.vs.cov Random parameters plotted against covariates, for Xpose 4
read.cwres.data Compute the Conditional Weighted Residuals
read.lst Read NONMEM output files into Xpose 4
read.lst6 Read NONMEM output files into Xpose 4
read.lst7 Read NONMEM output files into Xpose 4
read.nm.tables Reading NONMEM table files
read.npc.vpc.results Read the results file from a Numerical or Visual Predictive Check run in PsN
read.phi Read NONMEM output files into Xpose 4
read.TTE.sim.data Read (repeated) time-to-event simulation data files.
read.vpctab Read the vpctab file from PsN into Xpose
reset.graph.par Resets Xpose variable definitions to factory settings
reset.variables Resets Xpose variable definitions to factory settings
residual.diagnostics.menu Classic menu functions for Xpose 4
runsum Print run summary in Xpose 4
runsum.print Classic menu functions for Xpose 4

-- S --

SData Extract data from an xpose.data object.
SData<- Extract data from an xpose.data object.
set.doc Functions changing miscellaneous parameter settings in Xpose 4
setup.PPI Internal functions for the VPC
simpraz.xpdb Simulated prazosin Xpose database.
simprazExample Function to create files for the simulated Prazosin example in Xpose
sqrtm Compute the Conditional Weighted Residuals
struct.gof.menu Classic menu functions for Xpose 4
structural.diagnostics.menu Classic menu functions for Xpose 4

-- T --

table.file.read.settings.menu Classic menu functions for Xpose 4
tabulate.parameters Tabulate the population parameter estimates
test.xpose.data Data functions for Xpose 4

-- V --

vpc.npc.menu Classic menu functions for Xpose 4

-- W --

wres.dist.hist Histogram of weighted residuals (WRES), for Xpose 4
wres.dist.qq Quantile-quantile plot of weighted residuals (WRES), for Xpose 4
wres.vs.cov Weighted residuals (WRES) plotted against covariates, for Xpose 4
wres.vs.idv Population weighted residuals (WRES) plotted against the independent variable (IDV) for Xpose 4
wres.vs.idv.bw Box-and-whisker plot of weighted residuals vs the independent variable for Xpose 4
wres.vs.pred Population weighted residuals (WRES) plotted against population predictions (PRED) for Xpose 4
wres.vs.pred.bw Box-and-whisker plot of weighted residuals vs population predictions for Xpose 4

-- X --

xlabel Extract and set labels for Xpose data items.
xlabel<- Extract and set labels for Xpose data items.
xp.akaike.plot GAM functions for Xpose 4
xp.boot.par.est Compare parameter estimates for covariate coefficients
xp.boot.par.est.corr Correlations between covariate coefficients
xp.check.scope GAM functions for Xpose 4
xp.cook GAM functions for Xpose 4
xp.distr.mod.size Plot of model size distribution for a bootgam or bootscm
xp.dofv.plot OFV difference (optimism) plot.
xp.gam GAM functions for Xpose 4
xp.get.disp Stepwise GAM search for covariates on a parameter (Xpose 4)
xp.inc.prob Inclusion frequency plot
xp.inc.prob.comb.2 Inclusion frequency plot for combination of covariates.
xp.inc.stab.cov Inclusion stability plot
xp.incl.index.cov Plot of inclusion index of covariates.
xp.incl.index.cov.comp Inclusion index individuals, compare between covariates.
xp.incl.index.cov.ind Individual inclusion index
xp.ind.inf.fit GAM functions for Xpose 4
xp.ind.inf.terms GAM functions for Xpose 4
xp.ind.stud.res GAM functions for Xpose 4
xp.plot GAM functions for Xpose 4
xp.scope3 GAM functions for Xpose 4
xp.summary GAM functions for Xpose 4
xpose The Xpose Package
xpose.ask.for.filename Function to ask the user for the name of a file
xpose.ask.for.lst Function to ask the user for the name of a file
xpose.ask.for.mod Function to ask the user for the name of a file
xpose.bin Data functions for Xpose 4
xpose.calculate.cwres Compute the Conditional Weighted Residuals
xpose.create.label Functions to create labels for plots
xpose.create.title Functions to create labels for plots
xpose.create.title.hist Functions to create labels for plots
xpose.create.title.text Create Xpose title text for plots.
xpose.data Creates an Xpose data object
xpose.data-class Class xpose.data
xpose.dev.new Create a new graphical device for an Xpose plot.
xpose.gam Stepwise GAM search for covariates on a parameter (Xpose 4)
xpose.license.citation Displays the Xpose license and citation information
xpose.logTicks Functions to create nice looking axes when using Log scales.
xpose.multiple.plot Create and object with class "xpose.multiple.plot".
xpose.multiple.plot.default Xpose 4 generic function for plotting multiple lattice objects on one page
xpose.multiple.plot.title Functions to create labels for plots
xpose.panel.bw Default box-and-whisker panel function for Xpose 4
xpose.panel.default Default panel function for Xpose 4
xpose.panel.histogram Default histogram panel function for Xpose 4
xpose.panel.qq Default QQ panel function for Xpose 4
xpose.panel.splom Scatterplot matrix panel function for Xpose 4
xpose.plot.bw The generic Xpose functions for box-and-whisker plots
xpose.plot.default The Xpose 4 generic functions for continuous y-variables.
xpose.plot.histogram The Xpose 4 generic functions for continuous y-variables.
xpose.plot.qq The generic Xpose functions for QQ plots
xpose.plot.splom The Xpose 4 generic functions for scatterplot matrices.
xpose.prefs-class Class "xpose.prefs"
xpose.print Prints the contents of an Xpose data object
xpose.read Imports Xpose graphics settings from a file to an Xpose data object.
xpose.stack Generic internal functions for Xpose 4
xpose.string.print Print a pretty string.
xpose.VPC Visual Predictive Check (VPC) using XPOSE
xpose.VPC.both Xpose Visual Predictive Check (VPC) for both continuous and Limit of Quantification data.
xpose.VPC.categorical Xpose visual predictive check for categorical data.
xpose.write Exports Xpose graphics settings to a file.
xpose.xscale.components.log10 Functions to create nice looking axes when using Log scales.
xpose.yscale.components.log10 Functions to create nice looking axes when using Log scales.
xpose4 The Xpose Package
xpPage Structured goodness of fit diagnostics.
xsubset Extract or set the value of the Subset slot.
xsubset<- Extract or set the value of the Subset slot.
xvardef Extracts and set Xpose variable definitions.
xvardef<- Extracts and set Xpose variable definitions.