GSEA.Hotelling {SAGx} | R Documentation |
Based on a list of gene sets, e.g. pathways, in terms Affymtrix identifiers, these sets are ranked with respect to regulation in between two groups of chips.
GSEA.Hotelling(probeset = probeset, X = x, Y = y, pway = kegg, cutoff = 5)
probeset |
the Affymetrix identifiers |
X |
data for group 1 |
Y |
data for group 2 |
pway |
a list where each component contains a vector with probeset IDs |
cutoff |
Gene sets with less than cutoff members are excluded |
A list with the component score, pvalue, corr.pval.
Experimental function
Per Broberg
Yan Lu, Peng-Yuan Liu, Peng Xiao and Hong-Wen Deng : Hotelling's T2 multivariate profiling for detecting differential expression in microarrays, Bioinformatics, 2005, Vol.21, no.12