SRMA Analysis of Array-based Sequencing Data


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Documentation for package ‘SRMA’ version 1.0.0-1

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all.qn Normalized exon level data
amp.spec.qn Quantile normalization function on amplicons
ampmap Mapping between amplicons and exons
badamp Matrix for finding out the bad amplicons
calc.pp.bp Function for calculating posterior probablilities for a list of base positions
calc.pp.bp.2 Function for second round calculation of posterior probablilities for a list of base positions.
call.genotype Wrapper function of performing multi-array analysis
call.ref.base Function for a naive base caller used to calculate reference call rate
celint.qn quantile normalized intensities for each base
correct.lr Function for performing the adjustment of logratios using linear regression
correct.lr.singlebp Function for correcting logratios for single chip with determined principal alternative alelles.
cross.chip Function for cross-chip genotype calling.
dbsnp.info Example dbSNP dataset used in SRMA pipeline of analyzing array-based sequencing array
explore.qc Function for plotting qc measures for individual sample
find.badamps Function for finding bad amplicons
find.best.fit Function to select the best model fit
find.indels Function to find insertion/deletions.
get.delta.sigma Function for getting delta and sigma for each base
get.delta.sigma.qn Wrapper function for getting quantitle normalized delta and sigma for each base
get.intensity Function for getting raw or quantile normalizated intensities for each base
get.qc.measures.amplevel Function for calculatig amplicon specific QC measures
get.qc.measures.baselevel Function for preparing the measures used for quality assessment of DNA targets and resequencing arrays
get.qm Function for calculating quality measures for an amplicon
initialize-method Class "SRMAResults"
normalized.base.measures A high-level function for getting delta and sigma for each base
post.process Wrapper function for output analysis
quality.control A high-level function for identifying bad amplicons using raw intensities from CEL files
ref.info Example dataset containing reference allele information that are used in SRMA pipeline of analyzing array-based sequencing array
reorg.dat Normalized dataset for downstream analysis
reorganize.datafiles Function for reorganizing normalized data into array formats
sd.adj.dat Normalized dataset
show-method Class "SRMAResults"
single.array.lm.all.alleles A function for adjusting for logratios for all bases on a single array
single.chip.posterior.prob Wrapper function for adjustment of logratios for all bases using linear model
srma Function for Sequencing Robust Multi-array Analysis.
SRMAResults-class Class "SRMAResults"
summary-method Class "SRMAResults"
write.srma Function to write final SNV calls and Indel calls to tables