UBCRM is a R package containing functions to simulate and conduct dose escalation phase I studies.


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Documentation for package ‘UBCRM’ version 1.0

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UBCRM-package UBCRM is a R package containing functions to simulate and conduct dose escalation phase I studies.
ail1 Functions to calculate the appropriated dose level singletons.
ail2 Functions to calculate the appropriated dose level singletons.
aip Functions to calculate the appropriated dose level singletons.
ait1 Functions to calculate the appropriated dose level singletons.
ait2 Functions to calculate the appropriated dose level singletons.
CreData Creates a CRM dataframe.
Crm Dose escalation with the Continual Reassment Method
fl Density functions
fp Density functions
ft Density functions
Ll Likelihood functions
Lp Likelihood functions
Lt Likelihood functions
psil Dose-Toxicity modelisation functions
psip Dose-Toxicity modelisation functions
psit Dose-Toxicity modelisation functions
sim3p3 Simulation of one dose esclation study with the classical 3+3 design.
simCrm Simulation of one dose esclation study with the Continual Reassment Method.
ssim3p3 Simulation of n dose-escalation study with the 3+3 design
ssimCrm Simulation of n dose-escalation study with the Continual Reassment Method.
troisPtrois Dose escalation with the 3+3 design
UBCRM UBCRM is a R package containing functions to simulate and conduct dose escalation phase I studies.
updata update the crm dataframe after new patient's collected datas.