typeIerr {AGSDest}R Documentation

type I error rate of a GSD

Description

typeIerr is a function that computes the type I error rate of a GSD.

Usage

typeIerr(GSD)

Arguments

GSD object of the class GSTobj or list with the following elements: K = number of stages, a = vector with futility boundaries (not supported yet), b = rejection boundaries, t = vector with information fractions; see example blow.

Value

typeIerr returns the type I error rate of a GSD.

Author(s)

Niklas Hack niklas.hack@meduniwien.ac.at and Werner Brannath werner.brannath@meduniwien.ac.at

References

O'Brien, PC, Fleming, TR (1979) ''A multiple testing procedure for clinical trials'', Biometrics, 35 , 549-556

Schoenfeld, D (2001) ''A simple Algorithm for Designing Group Sequential Clinical Trials'', Biometrics, 27, 972-974

See Also

GSTobj

Examples

##The following calculates the type I error rate of a GSD. 

GSD<-list(K=4,a=rep(-8,4),b=c(4.333,2.963,2.359,2.014),
t=c(0.25,0.5,0.75,1),Imax=0.22)

typeIerr(GSD)

[Package AGSDest version 1.0 Index]