caMonoExp {CalciOMatic}R Documentation

MonoExponential Time Course of Intracellular Calcium Concentration

Description

The function caMonoExp returns a vector of intracellular calcium concentration ([Ca^2+]) vs time values t. A dCa jump occurs at tOn, followed by a monoexponential return to baseline value Ca0, with time constant tau.

Usage

caMonoExp(t = 1, tOn = 1, Ca0 = 0.05, dCa = 0.1, tau = 3)

Arguments

t a vector of time values at which [Ca^2+] is computed (in s)
tOn the time of the [Ca^2+] jump (in s)
Ca0 the baseline [Ca^2+] (in muM)
dCa the [Ca^2+] jump occuring at tOn (in muM)
tau the time constant of the [Ca^2+] monoexponential return to baseline (in s)

Value

A vector containing the [Ca^2+] values. The vector has the two following attributes:

Time a copy of argument t
tOn a copy of argument tOn

Author(s)

Sebastien Joucla sebastien.joucla@parisdescartes.fr

See Also

caBiExp, caMonoBiExpFromIG

Examples

  ## Simulate a monoexponential calcium transient
  Ca <- caMonoExp(t    = seq(0,10,0.1),
                  tOn  = 2,
                  Ca0  = 0.25,
                  dCa  = 1,
                  tau  = 2)

  ## Plot the calcium transient vs. time
  plot(attr(Ca,"Time"),Ca,type="l")

  ## Add a vertical dashed line at tOn
  abline(v = attr(Ca,"tOn"), lty = 2)

[Package CalciOMatic version 1.1-3 Index]