ABT {Rassoc}R Documentation

The allelic based test

Description

This function conducts the allelic based test to a 2 by 3 case-control contingency table and reports the test statistics and associated p-value.

Usage

ABT(data)

Arguments

data data is a 2 by 3 case-control contingency table. The first and second rows represent the case group and control group respectively. The first, second and third columns represent the genotypes of a susceptibility diallelic marker containing 0, 1 and 2 risk allele respectively. Thus, the numbers in this table represent the genotype counts belonging to the corresponding genotypes and case-control status.

Value

statistic the statistic of the allelic based test
p.value the associated p-value of the allelic based test

References

Sasieni, PD(1997). From genotypes to genes: doubling the sample size. Biometrics 53, 1253-1261.

Zang Y, Fung WK and Zheng G(2009). Simple Algorithms to calculate the asymptotic null distribution for MAX3 and genetic model selection in case-control genetic association studies in R. Journal of Statistical software (revised).

See Also

caco

Examples

library(Rassoc)
data(caco)
ex=matrix(caco[1,],nrow=2,byrow=TRUE)
## ex is an example of a 2 by 3 case-control contingency table. 
ABT(ex)
## Conduct the allelic based test to dataset ex. 
## The allelic based test
## data:  ex 
## statistic = -5.4903, p-value = 4.013e-08
## The statistic of the test is -5.4903.
## The associated p-value of the test is 4.013e-08.

[Package Rassoc version 1.01 Index]