HIV/AIDS SI data {mstate}R Documentation

Data from the Amsterdam Cohort Studies on HIV infection and AIDS

Description

A data frame of 329 homosexual men from the Amsterdam Cohort Studies on HIV infection and AIDS. The included variables are

patid
Patient identification number
time
Time in years from HIV infection to either SI appearance, AIDS, or last follow-up
status
Event indicator; 0 = censored, 1 = AIDS, 2 = SI appearance
cause
Failure cause; factor with levels "event-free", "AIDS", "SI"
ccr5
CCR5 genotype; factor with levels "WW" (2 wild-type alleles), "WM" (1 (or possibly two) mutant alleles)

Usage

data(aidssi)

Format

A data frame, see data.frame.

Details

This data was used in the tutorial on competing risks and multi-state models (Putter, Fiocco, Geskus, 2007). For more information refer to the tutorial or to the original papers (Geskus et al., 2000, 2003).

References

Geskus RB (2000). On the inclusion of prevalent cases in HIV/AIDS natural history studies through a marker-based estimate of time since seroconversion. Statistics in Medicine 19, 1753–1769.

Geskus RB, Miedema FA, Goudsmit J, Reiss P, Schuitemaker H, Coutinho RA (2003). Prediction of residual time to AIDS and death based on markers and cofactors. Journal of AIDS 32, 514–521.

Putter H, Fiocco M, Geskus RB (2007). Tutorial in biostatistics: Competing risks and multi-state models. Statistics in Medicine 26, 2389–2430.


[Package mstate version 0.2.3 Index]