A Bayesian Dose-Finding Design using Pharmacokinetics(PK) for Phase I Clinical Trials

Documentation for package ‘dfpk’ version 2.1.0

dfpk-package	A Bayesian Dose-Finding Design using Pharmacokinetics(PK) for Phase I Clinical Trials.
AUC_estim	Estimation of the area under the curve, AUC.
dfpk	A Bayesian Dose-Finding Design using Pharmacokinetics(PK) for Phase I Clinical Trials.
Dose-class	An S4 class to present the next recommended dose level in an ongoing trial.
dosefinding-class	An S4 class to represent a dosefinding results.
dtox	Dose finding method DTOX.
invlogit	Inverse logistic functions.
nextDose	Next dose determination of a phase I clinical trial.
nsim	Simulate one or more Phase I clinical trial(s) using the PK measure in the dose finding design.
pk.estim	The pharmacokinetic's (PK) measure of exposure.
pkcov	Dose finding method PKCOV.
pkcrm	Dose finding method PKCRM.
pklogit	Dose finding method PKLOGIT.
pkpop	Dose finding method PKPOP.
pktox	Dose finding method PKTOX.
plotConc	The generic function of plot.conc.
plotConc-method	The graphical representation of the drug's concentration in the plasma at time t after the drug administration.
plotDose	The generic function of the plot.dose.
plotDose-method	The graphical representation of dose escalation for each patient in the trial.
scen-class	An S4 class to represent a simulated scenarios.
scenarios	Generate new data from a scenarios.
show-method	S4 Methods for Function 'show'
show-methods	S4 Methods for Function 'show'
stan_f	The data stan_f includes all the Stan models that dfpk package uses.