Repeated Measurement Design for Phase I Clinical Trial


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Documentation for package ‘phase1RMD’ version 1.0.5

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eff_dat Patient efficacy data
parm Create prior for the phase 1 dose-finding model
patdata Patient toxicity data
probaT The probability matrix of toxicity events
RunRMD Toxicity-based Dose estimation for the next patient cohort.
RunRMDEff Toxicity and Efficacy-based Dose estimation for the next patient cohort.
SimRMD Simulate trial characters of the phase I dose-finding design.
SimRMDEff Simulate trial characters of the phase I dose-finding design using toxicity and efficacy data.
tox_dat Patient toxicity data
tox_matrix Probability matrix for toxicity