hla.demo {haplo.score}R Documentation

HLA Gene Variantion and Serologic Response to Measles Vaccination

Description

This data set gives markers of HLA gene variantion and antibody levels in response to measles vaccination for 220 unrelated subjects, from a study by the Mayo Clinic.

Usage

data(hla.demo)

Format

A data frame containing 220 rows and 10 columns:

resp
quantitative antibody response to measles vaccination
resp.cat
a factor with levels "low", "normal", "high", for categorical antibody response
male
sex code with 1="male" , 0="female"
age
age (months) at immunization

The remaining variables are genotypes for 3 HLA loci, with a prefix name (e.g., "DQB") and a suffix for each of two alleles (".a1" and ".a2").

Source

Poland G, Ovsyannikova I, Jacobson R, Vierkant R, Jacobsen S, Pankratz V, Schaid D (2002) Identification of an association between HLA class II alleles and low antibody levels after measles immunization. Vaccine 20:430?438


[Package haplo.score version 1.0.2 Index]