Utility {qtlDesign}R Documentation

Utility functions

Description

Utility functions

Usage

recomb(d)
genetic.dist(theta)
pmixnorm(x,mean=c(0,0),sd=c(1,1),mix.prop=0.5,level=0)
prop2delta.bc(prop)
delta2prop.bc(delta)
prop2delta.f2(prop,model)
delta2prop.f2(delta,model)
prop2gv(prop)
gv2prop(gv)

Arguments

d Genetic distance in Morgans
theta Recombination fraction
x Real number
mean Means of component mixtures
sd Standard deviations of component mixtures
mix.prop Mixing proportion
level Subtracting constant
prop Proportion of variance explained by a QTL
delta QTL effect size
model Type of genetic model
gv Genetic variance

Details

Value

recomb returns the recombination fraction corresponding to a genetic distance in Morgans. genetic.dist returns the genetic distance in Morgans for a recombination fraction. pmixnorm returns the probability mixture of two Normal distributions with means given by mean, standard deviations sd, and mixing proportions mix.prob, is less than x. prop2delta.bc returns the QTL effect from the proportion of variance explained for a backcross. delta2prop.bc returns the QTL effect from the proportion of variance explained in a backcross. prop2delta.f2 returns the QTL effect from the proportion of variance explained and genetic model for a F2 intercross. delta2prop.f2 returns the QTL effect from the proportion of variance explained and the genetic model in an F2 intercross. prop2gv returns the genetic variance (as a fraction of the environmental variance) given the proportion of variance explained by a QTL. gv2prop performs the inverse function.

Note

We assume Haldane mapping function for the genetic distance.

Author(s)

Saunak Sen, Jaya Satagopan, and Gary Churchill

References

Sen, Satagopan, and Churchill (2004), QTL study design from an information perspective, http://repositories.cdlib.org/cbmb/QTLdesign.

See Also

missinfo

Examples

recomb(0.1)
genetic.dist(0.1)
prop2delta.bc(0.1)
delta2prop.bc(0.1)

[Package qtlDesign version 0.32 Index]