Pathway analysis methods for genomewide association data


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Documentation for package ‘PAGWAS’ version 1.0

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PAGWAS-package Pathway analysis methods for genomewide association data
create.pathway.matrix Creates a pathway matrix
FM.chi.pvalue Calculates the Fisher's method p-value for each tested pathway
genes A data-frame of 20 genes with their chromosomes and positions on the genome
genotypes Genotypes for 100 SNPs
list.of.parameters A list with possible hyper-parameters for NBF
NBF Normal/Bayes factors (NBF) method for finding associated pathways
PAGWAS Pathway analysis methods for genomewide association data
pathways A list of 2 pathways with their gene members
return.a.SNAL Returns the hyper-parameter a of SNAL
return.bf.NBF Returns the Bayes factor threshold of NBF
return.hyperparameters.NBF Returns the four hyper-parameters of NBF
return.s2.SNAL Returns the s2 tuning parameter of SNAL
roc.convex Computes the area under a ROC curve
SNAL Sparse Normal/Adaptive lasso (SNAL) method for finding associated pathways
SNPs A data-frame of 100 SNPs with their chromosomes and positions on the genome
snps.to.genes Assigns SNPs to genes according to their physical distance
snps.to.pathways Assigns SNPs to pathways