obese {FunNet}R Documentation

Gene Expression Profiling of the Human White Adipose Tissue in Obese Subjects

Description

This data set resulted from microarray experiments performed on human white adipose tissue comparing the expression profiles in obese subjects and lean controls. Please see the references provided below for further experimental details.

Usage

data(obese)

Format

Three data frames containing significant genes up-regulated or down-regulated in human WAT of obese subjects and a reference list with all the genes tested for differential expression during this experiment.

Source

http://corneliu.henegar.info/FunNet.htm

References

1. Clement K, Viguerie N, Poitou C, Carette C, Pelloux V, Curat CA, Sicard A, Rome S, Benis A, Zucker JD et al: Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J 2004, 18(14):1657-1669.

2. Henegar C, Tordjman J, Achard V, Lacasa D, Cremer I, Guerre-Millo M, Poitou C, Basdevant A, Stich V, Viguerie N, Langin D, Bedossa P, Zucker J-D, Clement K. Adipose tissue transcriptomic signature highlights the pathologic relevance of extracellular matrix in human obesity. In positive revision in Genome Biology (October 2007).

3. GEO accession number: GSE9153. http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9153.

See Also

FunNet.


[Package FunNet version 1.00-6 Index]