obese {FunNet} | R Documentation |
This data set resulted from microarray experiments performed on human white adipose tissue comparing the expression profiles in obese subjects and lean controls. Please see the references provided below for further experimental details.
data(obese)
Three data frames containing significant genes up-regulated or down-regulated in human WAT of obese subjects and a reference list with all the genes tested for differential expression during this experiment.
http://corneliu.henegar.info/FunNet.htm
1. Clement K, Viguerie N, Poitou C, Carette C, Pelloux V, Curat CA, Sicard A, Rome S, Benis A, Zucker JD et al: Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J 2004, 18(14):1657-1669.
2. Henegar C, Tordjman J, Achard V, Lacasa D, Cremer I, Guerre-Millo M, Poitou C, Basdevant A, Stich V, Viguerie N, Langin D, Bedossa P, Zucker J-D, Clement K. Adipose tissue transcriptomic signature highlights the pathologic relevance of extracellular matrix in human obesity. In positive revision in Genome Biology (October 2007).
3. GEO accession number: GSE9153. http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9153.