aids {JM} | R Documentation |
A randomized clinical trial in which both longitudinal and survival data were collected to compare the efficacy and safety of two antiretroviral drugs in treating patients who had failed or were intolerant of zidovudine (AZT) therapy.
A data frame with 1408 observations on the following 9 variables.
patient
Time
death
CD4
obstime
drug
ddC
denoting zalcitabine and ddI
denoting didanosine.gender
female
and male
.prevOI
AIDS
denoting previous opportunistic infection (AIDS
diagnosis) at study entry, and noAIDS
denoting no previous infection.AZT
intolerance
and failure
denoting AZT intolerance and
AZT failure, respectively.
The data frame aids.id
contains the first CD4 cell count measurement for each patient. This data frame is used to
fit the survival model.
http://www.biostat.umn.edu/~brad/data.html, http://www.biostat.umn.edu/~brad/software.html
Goldman, A., Carlin, B., Crane, L., Launer, C., Korvick, J., Deyton, L. and Abrams, D. (1996) Response of CD4+ and clinical consequences to treatment using ddI or ddC in patients with advanced HIV infection. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 11, 161–169.
Guo, X. and Carlin, B. (2004) Separate and joint modeling of longitudinal and event time data using standard computer packages. The American Statistician 58, 16–24.
summary(aids.id)