HWE2sided {LDtests}R Documentation

P-values for three different tests of HWE

Description

Calculates conditional p-values proposed in Kulinskaya (2008) to overcome the problems of asymetric distributions, the Haldane 2-sided test as implemented by Wiggington et al (2005) and the 1-sided test for inbreeding.

Usage

HWE2sided(geno, qplot = F, title = NULL)

Arguments

geno Vector of genotype counts: no. heterozygotes followed by the nos. homozygotes
qplot If qplot is true the distribution of the null hypothesis is plotted
title Title for the plot

Value

pval.cond Conditional p-value
pval.H 2-sided Haldane p-value
pval.inbreed 1-sided test for inbreeding

Author(s)

Alex Lewin

References

Kulinskaya and Lewin 2008

See Also

HWE2sided.table

Examples

geno <- c(20,73,7)
HWE2sided(geno)

[Package LDtests version 1.0 Index]