mdd.mantelhaen.restricted {MDD} | R Documentation |
For a specified number of control responses in each strata, calculate all possible treatment response scenarios for which the test statistic will be signiifcant, and optionally (by default) print out a paragraph sumamrizing the results.
mdd.mantelhaen.restricted(placebo.size, treat.size, placebo.vals, alpha = 0.05, alternative = "two.sided", exact = TRUE, print.summary = TRUE)
placebo.size |
a vector with the number of subjects in each stratum assigned to the control group. |
treat.size |
a vector with the number of subjects in each stratum assigned to the treatment group. |
placebo.vals |
the number of responses to be observed in the control strata. |
alpha |
significance level. |
alternative |
indicates the alternative hypothesis and must be one of <code>"two.sided"</code>, <code>"greater"</code> or <code>"less"</code>. You can specify just the initial letter. |
exact |
a logical value indicating whether to do an exact conditional test or use the CMH test statistic. |
print.summary |
a logical indicating whether to print a paragraph summarizing the calculations. |
le |
All treatmenmt response scenarios for which the test statistic will be significant by virtue of the treatment response rate being less than the control response rate. |
gr |
All treatmenmt response scenarios for which the test statistic will be significant by virtue of the treatment response rate being greater than the control response rate. |
...
Run times for this program can be extremely large for trials with either a large number of strata or a large number of subjects.
For one-sided tests, at least one of the two components of the return value will automatically be empty!
This function does the same job as mdd.mantelhaen(..., to.file="file.Rdata")
followed
by extract.mdd.mantelhaen(..., from.file="file.RData")
, but much more quickly.
Don Barkauskas
See mantelhaen.test
for references.
mdd.mantelhaen
, extract.mdd.mantelhaen