MIfuns-package {MIfuns}R Documentation

Pharmacometric tools for data preparation, analysis, simulation, and reporting

Description

Pharmacometric tools for common data preparation tasks, stratified bootstrap resampling of data sets, NONMEM control stream creation/editing, NONMEM model execution, creation of standard and user-defined diagnostic plots, execution and summary of bootstrap and predictive check results, implementation of simulations from posterior parameter distributions, reporting of output tables and creation of a detailed analysis log. All functions are considered stable unless marked as beta.

Details

CLNR Delete files and directories; log what was deleted to a text file.
compute.cwres Compute the conditional weighted residuals (ind.cwres,read.cwres.data,is.cwres.readable).
CWRES Generate conditional weighted residual (CWRES) diagnostic plots as a pdf (cwres_1).
NONR Run NONMEM and create diagnostic plots.
PLOTR Generate diagnostic and/or covariate evaluation plots as a pdf or multiple pngs.
rlog Generate a combined run log from multiple NONMEM runs.
resample.data.frame Create replicate datasets by stratified sampling with replacement (as.csv.filename,resample.csv.filename).
metaSub.character Make multiple, systematic substitutions in text files (as.filename,metaSub.filename).
CreateParametersForSimulation Create parameters for simulation from uncertainity.
miTemporal Create date, time, and date-time objects with default behaviors appropriate for NMTRAN datasets.
bsa Calculate various clinical measurements: body size, etc. (bsa, bmi, ibw, lbm, crcl).
constant Test for nesting among factors(nests, nested.in, crosses).
naInContext View missing values in a broader context.
stableMerge Add keyed data to a dataframe safely.
css Calculate One-Compartment Model Properties (acr, cavg, cmax, cmin, ke, tmax, auc).
covplot Make "forest plots" of covariate effects, etc.
forbak Impute missing vector values(locf, nocb).
runhead Check some properties of vectors and data frames(maxChar, prev, sorted).
bin Calculate bin sizes and limits for a vector.
accept Document acceptance of an R installation (acceptance, packageCheck).

Package: MIfuns
Type: Package
Version: 3.2.9
Date: 2008-10-27
License: GPL

Author(s)

Developed by Metrum Institute (Bill Knebel, Tim Bergsma, and others). Maintainer: Bill Knebel <billk@metrumrg.com>

References

MIfuns package available from Metrum Institute website (http://metruminstitute.org/).


[Package MIfuns version 3.2.9 Index]