HU {TwslmSpikeWeight}R Documentation

Human placenta versus the Universal reference hybridization data

Description

This is a data frame consists 5 variables.

Usage

data(HU)

Format

A data frame with 75714 observations on 5 variables:
[,1] HUid gene identification number
[,2] HUslide slide number
[,3] HUblock block number within each slide
[,4] HUint total intensity 0.5log_2(RG)
[,5] HUratio intensity ratios log_2frac{R}{G}

where R is background adjusted signal intensity in the Cy5 channel, G is background adjusted signal intensity in the Cy3 channel.

Source

These data is the part of data set generated by human placenta versus the universal reference hybridization by Dr. Bento M. Soares lab in the University of Iowa. The data sets were used by Wang et al. (2006,2007) for the purpose of methodology demonstration.

References

Wang, D., Huang, J., Xie, H., Manzella, L., Soares, M. B., A robust two-way semi-linear model for normalization of cDNA microarray data,BMC Bioinformatics 2005, 6:14.

Wang, D., Zhang, C-H,Soares, M. B., Huang, J.(2007) Systematic approaches for incorporating control spots and data quality information to improve normalization of cDNA microarray data, Journal of Biopharmaceutical Statistics, 17:415-431.


[Package TwslmSpikeWeight version 1.0.1 Index]