WaveCGH-package {WaveCGH}R Documentation

Finding chromosomal gain/loss regions using wavelet method.

Description

It finds and plots DNA copy number gain/loss regions using wavelet method. Double implementation of MODWT confirms the presence of break points in the series. Bootstrapping procedure is used to call different regions to be normal, gain or loss regions.

Details

Package: WaveCGH
Type: Package
Version: 2.01
Date: 2008-09-27
License: GPL (>= 2)

Author(s)

M. S. Islam and A. I. McLeod Maintainer: <aimcleod@uwo.ca>

References

Islam, M. S. (2008). Periodicity, Change Detection and Prediction in Microarrays. Ph.D. Thesis, The University of Western Ontario.

Examples

data(arrayCGH)
# Finding break means for each chromosome
BreakMeansChr(arrayCGH[,1], arrayCGH[,2])
# Finding pvalues for testing means:
PvalBootMeanChr(arrayCGH[,1], arrayCGH[,2])

[Package WaveCGH version 2.01 Index]