NCA {bear} | R Documentation |
Noncompartmental analysis (NCA) approach is used to compute AUCs and the terminal elimination rate constants (lambda z) for drug plasma concentration. The linear trapezoidal method is applied to calculate AUC(time 0 to the last measurable Cp). The extrapolated AUC (from time of the last measurable Cp to time infinity) is equal to the last measurable Cp divided by lambda z.