sphase {maxstat} | R Documentation |
S-phase fraction of tumor cells in breast cancer patients.
data(sphase)
This data frame contains the following columns:
1
event)The data have been used to address the question whether a simple cutpoint in S-phase fraction can be used to discriminate between patients with good and bad prognosis (for example in Hothorn & Lausen, 2003).
J. Pfisterer, F. Kommoss, W. Sauerbrei, D. Menzel, M. Kiechle, E. Giese, M. Hilgarth & A. Pfleiderer (1995). DNA flow cytometry in node positive breast cancer: Prognostic value and correlation to morphological and clinical factors. Analytical and Quantitative Cytology and Histology 7(6), 406–412.
Torsten Hothorn & Berthold Lausen (2003). On the Exact Distribution of Maximally Selected Rank Statistics. Computational Statistics & Data Analysis 43, 121–137.
data(sphase) maxstat.test(Surv(RFS, cens) ~ SPF, data=sphase, smethod="LogRank", pmethod="Lau94") maxstat.test(Surv(RFS, cens) ~ SPF, data=sphase, smethod="LogRank", pmethod="Lau94", iscores=TRUE) maxstat.test(Surv(RFS, cens) ~ SPF, data=sphase, smethod="LogRank", pmethod="HL") maxstat.test(Surv(RFS, cens) ~ SPF, data=sphase, smethod="LogRank", pmethod="condMC", B = 9999) plot(maxstat.test(Surv(RFS, cens) ~ SPF, data=sphase, smethod="LogRank"))