nf1 {qtlbook} | R Documentation |
Data from a backcross experiment on neurofibromatosis type I. All individuals carry the NPcis mutation, received either from their mother or from their father.
data(nf1)
An object of class cross
. See read.cross
for details.
Backcrosses (C57BL/6J x A/J) x C57BL/6J and C57BL/6J x (A/J x
C57BL/6J) with a total of 254 individuals. Individuals received the
NPcis mutation from either their mother or their father
(indicated by the phenotype from.mom
. The major phenotype,
affected
indicates whether the mice were affected (1) or
unaffected (0) with neurofibromatosis type 1.
Karlyne Reilly, Mouse Cancer Genetics Program, National Cancer Institute at Frederick, kreilly@ncifcrf.gov
Reilly, K. M., Broman, K. W., Bronson, R. T., Tsang, S., Loisel, D. A., Christy, E. S., Sun, Z., Diehl, J., Munroe, D. J. and Tuskan, R. G. (2006) An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model. Cancer Research 66, 62–68.
gutlength
iron
, myocard
,
ovar
, trout
data(nf1) plot(nf1)