fdr.an {varmixt}R Documentation

FDR analysis of variance mixture analysis results

Description

This functions computes the number of regulated genes at given level of FDR

Usage

fdr.an(data,Q=0.05,display=TRUE,lambda=seq(0,0.95,0.05))

Arguments

data A gene gene expression data object. The results of vm.analysis or vm.analysis.paired function
Q the fdr level
display if TRUE prints the number of regulated genes and corresponding p-values for the different methods on the screen
lambda Argument to the q-value function.

Details

If lambda=0, then the FDR is computed (Benjamini Hochberg). If lambda is set to its default, the the pFDR according to Storey is computed.

Value

a data frame with the number of genes regulated with the different analysis methods and the corresponding p-value

Author(s)

Paul Delmar

References

Benjamini, Y. and Y. Hochberg (1995). Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Statist. Soc. B 57(1), 289-300 Storey JD. (2002) A direct approach to false discovery rates. Journal of the Royal Statistical Society, Series B, 64: 479-498

See Also

vm.analysis, vm.analysis.paired, pval.an


[Package varmixt version 0.2-4 Index]