U2OS {waveclock}R Documentation

Luminescence measurements from U2-OS osteosarcoma cells

Description

This data set contains luminescence traces from osteosarcoma cells stably expressing a Bmal1-luciferase reporter. In each experiment the cells were transfected with siRNAs against circadian clock components.

Usage

U2OS

Format

A list containing the following time series objects: Fig.S1, Fig.S2AB, Fig.S2C, Fig.S2D, Fig.S2E, Fig.S2F, Fig.S2GI, Fig.S2H, siBmal1, siBmal1_Cry1, siClock, siCry1_Cry2, siCry1Cry2. Each column of these objects contains 721 measurements spaced 10 minutes apart. A very small proportion of missing data points (less than 1 per 4,000) have been imputed by linear interpolation.

References

Baggs, J. E., Price, T. S., DeHaro L., Panda, S., FitzGerald, G. A., and Hogenesch, J. B. Elucidating network structures of the circadian clock underlying robustness. Manuscript submitted for publication.


[Package waveclock version 1.0-3.1 Index]