mixlow method for assessing drug synergism


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Documentation for package ‘mixlow’ version 0.02.1

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mixlow-package Calculate synergism/antagonism indices based on concentration- response curve parameters
doLoewe Estimate Loewe indices and confidence intervals
doNlme Conduct nonlinear mixed-effects analysis of sigmoidal concentration- response data
doNls Conduct nonlinear least-squares analysis of sigmoidal concentration-response data
getCellLines Retrieve a vector of cell line names from data
getDrugs Retrieve a vector of drug names from data
getNlsParameterDefaults Generate a data frame of default values for nonlinear lest-squares analysis
getTrays Retrieve a vector of tray names from data
loeweData loeweData Dataset
mixlow Calculate synergism/antagonism indices based on concentration- response curve parameters
mixlowData mixlowData Dataset
nlmeData nlmeData Dataset
NlmePrintVarFunctions Print variance function options for nonlinear mixed-effects analysis
nlsData nlsData Dataset
plot.loeweData Plot a loeweData object obtained from Loewe analysis
plot.mixlowData Plot a mixlowData object
plot.nlmeData Plot nlmeData object obtained from nonlinear mixed-effects analysis
plot.nlsData Plot nlsData object obtained from nonlinear least-squares analysis
prepareData Prepares raw data for use by other functions
print.loeweData Prints a loeweData object obtained from Loewe analysis
print.mixlowData Print a mixlowData object
print.nlmeData Print a nlmeData object obtained from nonlinear mixed-effects analysis
print.nlsData Prints a nlsData object obtained from nonlinear least-squares analysis
readDataFile Read a formatted file of concentration-response data
summarizeData Print summary of data object
trayData trayData Dataset