Planning and Analyzing Dose Finding experiments


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Documentation for package ‘DoseFinding’ version 0.6-1

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DoseFinding-package Package overview
AIC.DRMod Calculate AIC, BIC or log-likelihood for a DRMod object
betaMod Built-in dose-response models in DoseFinding
betaModGrad Built-in dose-response models in DoseFinding
biom Biometrics Dose Response data
bootMCPMod Evaluate precision of dose estimate by nonparametric bootstrapping
calcBayesEst Calculates posterior estimates and posterior model probabilities for a set of candidate models.
calcCrit Calculate design criterion for a specified design.
calcOptDesign Function to calculate an optimal design
coef.DRMod Methods for DRMod and gDRMod objects
coef.gDRMod Methods for DRMod and gDRMod objects
critVal Calculate critical value for multiple contrast test
DoseFinding Package overview
DR-Models Built-in dose-response models in DoseFinding
DRMod and gDRMod methods Methods for DRMod and gDRMod objects
ED Calculate EDp estimator for a DRMod object
ED.DRMod Calculate EDp estimator for a DRMod object
emax Built-in dose-response models in DoseFinding
emaxGrad Built-in dose-response models in DoseFinding
exponential Built-in dose-response models in DoseFinding
exponentialGrad Built-in dose-response models in DoseFinding
fit.control Set control parameters for non-linear model fitting
fitDRModel Fit a non-linear regression model with linear covariates.
fullMod Calculate location and scale parameters for candidate set of models
genDFdata Simulate dose-response data
getBnds Calculates default bounds for non-linear parameters
getGrad Calculate the gradient for the non-linear part of a DRMod object
getInit Starting values for non-linear parameters.
getPars Calculate location and scale parameters
getUpdDesign Calculate Bayes estimates and optimal design for next cohort
gFitDRModel Generalized fitting of dose-response models to raw dose-response estimates
gMCPtest Generalized multiple contrast tests
guesst Calculate guesstimates based on prior knowledge
IBScovars Irritable Bowel Syndrome Dose Response data with covariates
intervals.DRMod Methods for DRMod and gDRMod objects
intervals.gDRMod Methods for DRMod and gDRMod objects
linear Built-in dose-response models in DoseFinding
linearGrad Built-in dose-response models in DoseFinding
linlog Built-in dose-response models in DoseFinding
linlogGrad Built-in dose-response models in DoseFinding
logistic Built-in dose-response models in DoseFinding
logisticGrad Built-in dose-response models in DoseFinding
logLik.DRMod Calculate AIC, BIC or log-likelihood for a DRMod object
LP Sensitivity analysis for misspecification of standardized model parameters in MCPMod
MCPMod Perform MCPMod analysis of a data set
MCPtest Perform model-based multiple contrast test
MED Calculate MED for a DRMod object
MED.DRMod Calculate MED for a DRMod object
migraine Migraine Dose Response data
modelMeans Calculate mean vectors for a given candidate set
mvtnorm.control Control options for pmvt and qmvt functions
planMM Calculate optimal contrasts and critical value for MCP test
plot.DRMod Methods for DRMod and gDRMod objects
plot.fullMod Plot method for fullMod objects
plot.gDRMod Methods for DRMod and gDRMod objects
plot.LP Plot method for LP objects
plot.MCPMod Plot MCPMod model fits
plot.planMM Plotting a planMM object
plot.powerMM Plot method for powerMM objects
plotModels Plot candidate models
powCalc Calculate the power for the multiple contrast test
powerMM Calculate power for different sample sizes
powerScenario Calculates the power for an planMM object under a particular alternative scenario
predict.DRMod Methods for DRMod and gDRMod objects
predict.gDRMod Methods for DRMod and gDRMod objects
predict.MCPMod Predict a MCPMod object.
print.LP Sensitivity analysis for misspecification of standardized model parameters in MCPMod
print.MCPMod Perform MCPMod analysis of a data set
print.planMM Calculate optimal contrasts and critical value for MCP test
print.sampSize Sample size calculations for MCPMod
print.summary.MCPMod Perform MCPMod analysis of a data set
quadratic Built-in dose-response models in DoseFinding
quadraticGrad Built-in dose-response models in DoseFinding
rndDesign Round a continuous design to integer values.
sampSize Sample size calculations for MCPMod
sigEmax Built-in dose-response models in DoseFinding
sigEmaxGrad Built-in dose-response models in DoseFinding
summary.MCPMod Perform MCPMod analysis of a data set
vcov.DRMod Methods for DRMod and gDRMod objects
vcov.gDRMod Methods for DRMod and gDRMod objects