Genetics ToolboX


[Up] [Top]

Documentation for package ‘gtx’ version 0.0.3

Help Pages

align.snpdata.coding Update genotype coding when there are coded allele designation flips.
allelesAB Paste together (vectors of) A and B alleles after sorting alphabetically.
as.snpdata Class for SNP genotype and phenotype data.
bp.scores Genetic risk scores for blood pressure.
cad.scores Genetic risk scores for coronary artery disease risk
coeff.extract Coefficient extractor for fitted models.
combine.moments2 Builds a matrix of second moments for a set of individuals, from the matrices of second moments for all constituent subsets of individuals.
est.moments2 Estimate regression coefficients using quadratic approximation to likelihood function.
gls.approx.logistic Calculate weights and transformed phenotype so that one iteration of generalised least squares approximates a logistic regression.
grs.filter.Qrs Filter SNPs for inclusion in genetic risk score using heterogeneity test.
grs.make.scores Make genetic risk scores from individual-level data.
grs.onesnp.apply Convenience tool to fit a series of single-SNP models.
grs.plot Diagnostic plot for genetic risk score calculation from summary statistics.
grs.summary Genetic risk score calculation from summary statistics.
gtx Genetics ToolboX
gtx.params Parameter format for multi-SNP analyses
hapmap.read.haplotypes Read hapmap haplotypes.
hapmap.snpdata Extract individual level snp/haplotype data from HapMap
height.scores Genetic risk score for height.
is.snpdata Class for SNP genotype and phenotype data.
lipid.scores Genetic risk scores for serum lipid levels
lm.moments2 Fit normal linear model using pre-built matrix of second moments.
magic.scores Genetic risk scores for glucose/insulin traits.
make.moments2 Build matrix of second moments from subject-specific data.
mthfr.params Simulated example finemapping genotype and phenotype data.
mthfrex Simulated example finemapping genotype and phenotype data.
read.snpdata.impute Read genotype dosages in the format output by IMPUTE.
read.snpdata.mach Read genotype dosages in the format output by MACH
read.snpdata.plink Read genotype dosages in the format output by PLINK.
snpdata Class for SNP genotype and phenotype data.
stepdown.moments2 Stepwise downward model selection using summary statistic matrix.
stepup.moments2 Stepwise upward model selection using summary statistic matrix.
summary.snpdata Class for SNP genotype and phenotype data.
t2d.scores Genetic risk scores for type 2 diabetes risk.
t2dex Simulated example genotype and longitudinal phenotype data.